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Cure For Heart Disease – True Testimonial
Update Nov. 28, 2006

Background: 1995 first of four heart attacks, quadruple bypass, stent Operations, five total operations to date. I declined a pacemaker implant (TEST) in Dec. of 2003.
Continued problem: from 1995 to 2003 numerous heart attacks, operations, feeling almost hopeless. I had tried numerous things that my doctors recommended. I became a strict vegan, no: eggs, chicken, fish, etc. did not smoke, etc. these practices were put into place immediately after my first heart attack and quadruple bypass in fall of 1995 for a period of over five years.

On the edge of death: chest pain, no energy, the feeling of doom, fall of 2005. I did not think I would be alive on Christmas or new year of 2005. my health wasn’t good, but I was in a steep decline at about the end of ’05.

Rediscovery of vitamin c: I searched the Internet for anything that would help me stay alive. I was desperate, too sick to work, no health insurance.

Course change: Pauling protocol. I don’t know if I rediscovered Pauling before or after I discovered the vitamin c foundation web site. I ordered all of Pauling’s books at the local library and read them all. this was about the beginning of 2006, or the end of 2005. many years ago I remember seeing Pauling on TV. and hearing about his work with Vitamin c. I also recall the media in general as labeling him in a very subtle way a “kook”. this probably caused me to not read his work back
in those years. I started taking ten grams of vitamin c every day, spread out five times during the day, about the time i rediscovered Pauling and read his books on vitamin c. I continued to find everything I could about vitamin c. I learned on the vitamin c foundation about other supplements. I also discovered the rich history of vitamin c research. There were many people I read, including Dr. Rath.

I was soon taking as much vitamin c as I could tolerate, 18 grams, plus I added some other supplements. Being a very skeptical person I only started the Pauling protocol with ten grams of c and nothing else.

Currently taking each day, spread out:

vit. C 14 grams (had cut this down once before from 18 to 16)
Lysine 5 grams
Proline 1 gr
Natural E 2000iu
Q10 100 mg
B3 500mg, just recently raised from 250mg
B6 100mg (in the form of a super B complex)
Multi vitamin/mineral
vit. A 24,000iu
Argenine 1 gram
Magnesium 250mg
Vit.K 100mg
L Carnitine 250mg
Taurine 500mg
Omega 3 2000mg, just added this a week ago.
Sea Salt: Himalayan Pink (to season food)

Biggest surprise: I was doing very hard physical work for over two weeks just recently, lots of pain in muscles from head to toe…but NO CHEST, or HEART PAIN!

Recent blood pressure: 122 over 72, a big surprise and I thought it was a mistake. I had just had a big dinner with friends a few hours before. This may have caused the reading to be lower. My “usual” bp is around 135 over 79 and this is continuing to drop, without any bp meds, or any heart meds in almost a year. I would like to see it 120 over 80. my resting pulse is still high at 100. (My records indicate a bp of over 147 over 95 while previously on bp and heart drugs)

Weight: I have been of average height and weight all of my life. I am now fifty two years old. Not until I read Atkins and started eating accordingly did I feel really
good with no hunger between meals or fatigue, like I always used to experience. The major benefit seems to be a drastic reduction in hydrogenated oil, etc. found in bakery and prepared food.

Other body changes: my skin has cleared up and looks great, I had a small amount of acne on my face for most of my life. My joints are less painful and more flexible. I feel much stronger and better than I have in over twenty years!

Diet: two eggs for breakfast almost every day with some meat. I minimize carb’s due to reading and understanding the Atkins books. Most of my carb’s now are in the form of fresh green veg. or fruit. I tried his diet and feel much better. I eat lots of meat, some fresh veggies, and lots of water. I had given up refined sugar many years before my first heart attack, but still had enjoyed sweet carbohydrate deserts.

Bad habits: although I no longer eat cookies and other bakery, I still love pizza and ice cream. I will over do it on carb’s on occasion and feel worse for it. I read labels and try to avoid hydrogenated oil (Check your pizza label) like the poison it is.

Future: health is great and getting better! I feel physically and mentally great! I think I’m going to be ok! I have also found an interest in vitamin B 17 and will look into this.

I would count this website (http://www.vitamincfoundation.org) and the posters on it, Dr. Levy’s new book, other writers (forgive me for not mentioning them all by name (the list is growing rapidly!), (but Owen has provided a very good list on this website)and let us not forget Dr. Linus Pauling who spent the last decades of his life in the study of and publication of information about vitamin c and it’s benefits to mankind.

The Cure for Heart Disease: Theory, History and Treatment

By Owen R. Fonorow, Copyright 2004

OVERVIEW

The theory that Cardiovascular Disease (CVD) is related to a deficiency of ascorbic acid (vitamin C) was first proposed by the Canadian physician G. C. Willis in 1953. Willis found that atherosclerotic plaques form over vitamin-C-starved vascular tissues in both guinea pigs and human beings. In 1989, after the discoveries of the Lp(a) cholesterol molecule (circa 1964) and its lysine binding sites (circa 1987), Linus Pauling and his associate Matthias Rath formulated a unified theory of heart disease and invented the cure.Vitamin C and lysine (and proline) in large amounts become Lp(a) binding inhibitors that restore vascular health and destroy atherosclerotic plaques.

THEORY

“Vitamin C is essential for the building of collagen, the most abundant protein built in our bodies and the major component of connective tissue. This connective tissue has structural and supportive functions that are indispensable to heart tissues, to blood vessels, –in fact, to all tissues. Collagen is not only the most abundant protein in our bodies, it also occurs in larger amounts than all other proteins put together. It cannot be built without vitamin C. No heart or blood vessel or another organ could possibly perform its functions without collagen. No heart or blood vessel can be maintained in a healthy condition without vitamin C.” Roger J. Williams

Vitamin C is ascorbic acid, (but it is not really a vitamin). The overwhelming majority of plants and animals make large amounts of ascorbic acid. Mammals synthesize it in the amount averaging 5,400 mg (when adjusted for body weight), and they make even more when under stress.  This is about 10-times the amount of CoQ10 that is synthesized in human beings, and roughly 100-times the U.S. Recommended Daily Allowance (RDA).

Homo Sapiens, like the guinea pig, fruit bat and the high-order primates, cannot synthesize vitamin C because of a missing enzyme. [*] These species must obtain the vitamin in the diet or die of scurvy. A mere 10 mg of vitamin C prevents acute scurvy in humans resulting in the long-held hypothesis that ascorbic acid is a vitamin, required only in minuscule amounts. Those few species that fail to synthesize ascorbic acid all suffer similar ‘heart disease’, a form of the disease that is not prevalent in other species.

Also, heart disease is a misnomer; the underlying disease process reduces the supply of blood to the heart and other organs leading to angina (“heart cramp”), heart attack, and stroke. The disease is characterized by scab-like build-ups that grow on the walls of blood vessels. The correct terminology for this disease process is chronic scurvy, a slower form of the classic vitamin C deficiency disease.

The hypothesis that CVD is ascorbic acid (vitamin C) deficiency disease was first conceived and tested in the early 1950s [*]. Willis devised a method of photographing plaques with X-rays and observed a strange phenomenon in his heart patients. Willis saw that atherosclerotic plaques were not uniformly distributed throughout the vascular system; rather these “blockages” are concentrated near the heart, where arteries are constantly bent or squeezed.

Another Canadian, Paterson, had found that the tissues of heart patients were generally depleted of ascorbate (vitamin C) [*], and it was well known that vitamin C is required for strong and healthy arteries. Willis reasoned that only the mechanical stress caused by the pulse could explain the typical pattern of atherosclerosis that he so often observed in different patients. To Willis, the body was laying down plaque precisely where it was needed in order to stabilize the vascular system.

By the late 1980s, medical researchers had made several intriguing discoveries. First came the discovery that heart disease begins with a lesion, a crack or stress fracture, in the arterial wall. The question became, and remains, as to the cause of these lesions in human beings since they do not arise in most other animals. Then a variant of the so-called “bad” LDL cholesterol called lipoprotein(a), or Lp(a) for short, was studied and found to be really bad. It is sticky because of receptors on the surface of the molecule called lysine binding sites. Work that led to the 1987 Nobel prize in medicine discovered that lysine (and proline) binding sites cause the formation of atherosclerotic plaques. Then, Beisiegel et. al. in Germany examined plaques post mortem and found only Lp(a), not ordinary LDL cholesterol. [*]

Matthias Rath, a medical student and member of the German team, immediately understood the importance of the Lp(a) cholesterol molecule (there are scores of similar lipoprotein molecules) and made the connection with vitamin C. Lp(a) was the genetic difference between beings that suffer cardiovascular disease and those that do not. Lp(a) had evolved only in species that do not make their own vitamin C – e.g. humans and guinea pigs.

Rath brought Lp(a) to the attention of Linus Pauling and was asked to join Pauling’s Institute of Science and Medicine. There Pauling and Rath repeated the earlier Willis experiments, but this time they monitored Lp(a). They discovered that it becomes elevated in guinea pigs deprived of vitamin C, but not in the controls. These experiments connecting elevated-Lp(a) with low serum vitamin C — and atherosclerosis, provide the experimental support for their unified theory. They realized that in most species, sufficient ascorbic acid will prevent stress fractures, but in those species that suffer chronic scurvy, Lp(a) had evolved to patch cracked blood vessels.

Linus Pauling believed that chronic scurvy can be prevented with a daily intake of between 3,000 to 10,000 mg or more vitamin C. This amount approximates what the animals synthesize, and matching animal production is the reason Pauling ingested 18,000 mg daily.

Pauling’s invention for destroying existing atherosclerotic plaques is a large amount of another essential nutrient, the amino acid lysine. Pauling filmed a video lecture in which he recommended that heart patients take between 2,000 and 6,000 mg of lysine daily with their vitamin C (more if serum Lp(a) is elevated). Neither vitamin C nor lysine has any known lethal dose.

HISTORY

In the early 1950s the Canadian doctor Willis theorized that that plaque build-up are the healing response to a repeated insult – the heartbeat. Willis observed that the build-up of atherosclerotic plaques was uniform, and not found throughout the vascular system. It appeared only in the large arteries near the heart where the blood pressure is greatest and where the artery is constantly stressed. He used high-school physics to compute that plaques form precisely where the mechanical forces were greatest on the arterial wall. Willis reasoned that these plaques only form overstress fractures when the intake of vitamin C is low.

Is heart disease a mechanical problem exacerbated by a vitamin C deficiency? Willis decided to find out. His experiment with guinea pigs is described in his landmark 1957 paper THE REVERSIBILITY OF ATHEROSCLEROSIS 

Guinea pigs are one of the few species which, like humans, do not make vitamin C. The pigs were divided into several groups; all groups were fed an identical diet except for the vitamin C. At first, vitamin C was restricted in all groups. The control group was sacrificed first and every guinea pig group was found to have atherosclerosis. The remaining groups were then given various amounts of vitamin C, having already induced atherosclerosis. Only half of these pigs were found to have atherosclerosis providing strong evidence that vitamin C can reverse existing disease. In the other experiments, groups of guinea pigs that are given almost 10-times the RDA, or roughly 5000 mg of vitamin C, adjusted for body weight, do not exhibit any sign of atherosclerosis.

Willis noted the similarity of the vitamin C deprived pig’s atherosclerotic lesions to the human lesions, and how unlike these lesions are to the “fatty streaks” that can be created in experimental animals fed ultra-high cholesterol diets.

From this experiment we know that a single factor, low vitamin C, can cause the atherosclerosis commonly found in humans.

Willis conducted experiments on his patients. He divided patients into two groups. One group was given 500 mg of vitamin C, three times daily. Remarkable for the 1950s, Willis was able to take pictures and “see” the inside of human arteries for the first time. From these pictures, it was determined that 60% of those taking vitamin C improved, that is, their plaques were reduced. In 30% the plaques remained about the same and in 10% he saw their plaques increase slightly. None of the control’s plaques were reduced. These results were promising, Willis in this technique, was well ahead of his time. However, the scientific and medical communities showed little interest in the Willis experiments.

We now know that 1500 mg of vitamin C is not enough. The Lp(a) molecule and its binding sites were unknown and the amino acid lysine was not employed. Also, there was a theoretical problem: All animals have heart beats, but they rarely suffer the same type of CVD as humans. How could the beating heart only cause the disease process in humans? Willis did not have the answer as to why human hearts and vascular systems were so different from most animals.

THE KEY TO THE PUZZLE – Lp(a)

Forty years after the Willis experiments, and after it was discovered that only one form of cholesterol — Lp(a) creates plaques over the arterial lesions [*] , the American Nobel chemist Linus Pauling, and his associate Matthias Rath, MD, formulated a new theory that unified vitamin C and Lp(a).

In their view, the strange Lp(a) molecule explained everything. Lp(a), the friend who may become a foe, has evolved to replace vitamin C only in the very few species that do not make their own vitamin C. The Lp(a) molecule is important for human health, in the absence of vitamin C, providing many of the same functions that the missing vitamin C would have provided.

Now the Willis “problem” had become a cornerstone of their theory: Lp(a) is an evolutionary adaptation or surrogate for low vitamin C which most animals do not require. Lp(a) provides an alternate way to strengthen and stabilize vitamin-starved arteries in species that cannot make the vitamin.

Inside the wall of every blood vessel lies the collagen girder shaped into a triple helix. Wrapped around the artery, like steel buried in a concrete highway, collagen provides the artery with its strength and stability. Collagen is a living tissue and needs to be replenished periodically. If vitamin C is present, collagen will be strengthened before the artery fractures. When vitamin C is not present, collagen continues to deteriorate and the arterial wall weakens. Surface disruptions will emerge, especially where the pulse is great. Strands of lysine and proline become exposed in these “pot-holes” along our most crowded vascular highways. The floating Lp(a) comes to the rescue; it is attracted to lysyl or prolyl strands in the pothole and binds with it, forming a patch, unless — something happens that makes it unattractive.

NULLIFYING THE LYSINE BINDING SITES – REVERSING HEART DISEASE.

As chronic scurvy progresses, the liver produces more Lp(a) molecules. As the number of Lp(a) molecules increases, they tend to deposit on top of existing plaque formations. When the healing process overshoots, the arteries narrow and the flow of blood is reduced.

This problem has a solution. The Lp(a) molecule has a finite number of lysine binding sites – points of attachment to lysine. Pauling’s invention – the cure for heart disease – is to increase the serum concentration of the amino acid lysine enough to make the Lp(a) unattractive. As more lysine enters the bloodstream, the probability increases that floating Lp(a) molecules will bind with it (rather than with the patches of plaques growing on the arterial walls.)

After all the Lp(a) molecule’s binding receptors are filled with the free lysine floating in the blood, the Lp(a) molecule becomes as harmless as ordinary LDL cholesterol.

Pauling and Rath called the substances that treat chronic scurvy and destroy existing plaques Lp(a) binding inhibitors. Vitamin C, to increase collagen production and to improve the health and strength of arteries, and lysine, to prevent and to dissolve Lp(a) plaques, are the primary binding inhibitors. These substances taken together are clinically effective.

Pauling and Rath have been awarded three U. S. patents for Lp(a) binding inhibitors that destroy atherosclerotic plaques in vitro and in vivo. [*]

The Lp(a) binding inhibitors become the Pauling Therapy for heart disease only at high dosages, between vitamin 3 to 18 g ascorbic acid and 3 to 6 g lysine. In his video, Pauling recounts the first cases where his high vitamin C and lysine therapy quickly resolved advanced cardiovascular disease in humans. The effect is so pronounced, and the inhibitors are so nontoxic, that Pauling doubted a clinical study was even necessary.

More than 10-years of consistent testimony[*] demonstrate that Pauling’s recommended dosages of the Lp(a) binding inhibitors are almost always effective reversing advanced heart disease within 10-days after achieving the recommended dosage. 

Recently, the amino acid proline was found to be an even more effective Lp(a) binding inhibitor than lysine in vitro. Adding between .5 and 2 g proline may be of significant additional benefit.

When serum Lp(a) is elevated, Lp(a) binding inhibitors can profoundly interfere with the disease process. Binding inhibitor formulas that include proline have been documented to lower Lp(a) in six to 14 months [*]. In cases where Lp(a) is not reduced, binding inhibitors become even more important regardless of their effect on serum Lp(a).

THE BASIC RECOMMENDATIONS FOR CONTROLLING HEART DISEASE

AUG 2004: UPDATED PROTOCOL HERE
Cardiologists have been kept in the dark about the vitamin C connection. Few cardiovascular drugs benefit heart patients. Several exacerbate heart conditions and should be eliminated in favor of the following orthomolecular protocols:

• Take Vitamin C as ascorbic acid or sodium ascorbate up to bowel tolerance (3 to 18 g) daily.
• Take Lysine. 2 to 3 g daily for prevention and from 3 to 6 g daily for the greatest therapeutic benefit.
• NEW: Eliminate man-made/processed fats, such as trans and hydrogenated fats, and supplement Omega-3 rich oils. “Research has shown that an Omega-3 Index of 8 percent to 10 percent reduces a person’s relative risk of death from coronary heart disease by 40 percent, and from sudden cardiac death by 90 percent.” This benefit probably results from restored insulin-mediated glucose/vitamin C uptake into cells. Note: Following an Atkins-style diet will eliminate most trans fats because these “poisons” appear mostly in processed carbohydrate foods such as cookies, crackers, snacks, etc. Butter is vastly supperior to margarine. Natural saturated fats are vastly superior to any fats or oils processed for longer shelf life.
• 
  NEW: Eliminate ordinary sugar and refined carbohydrates. New research confirms Dr. John Ely’s 30-year theory that sugar (glucose) competes with ascorbic acid (Vitamin C) for insulin-mediated uptake into cells. Taking sugar can effectively crowd out the Ascorbate. The effect of the Pauling Therapy is reportedly much more pronounced and immediate when sugar is eliminated.
• Take Proline from 250 mg to 2000 mg daily. (This added factor may lower elevated Lp(a) within 6 to 14 months.)
• Follow Paulings general heart and cardiovascular recommendations provided in his book HOW TO LIVE LONGER AND FEEL BETTER
  Linus Pauling’s Basic Vitamin Program

  Vitamin E – 800 to 3200 iu
  Vitamin A – 20,000 to 40,000 iu
  Super B-Complex, esp. Vitamins B6 and B3

• Supplement Coenzyme Q10 (100 – 300 mg) (High vitamin C and several vitamins will help stimulate your own synthesis of CoQ10 which is vital for proper heart function.)
• Supplement the mineral Magnesium (300 to 1500 mg) and avoid Manganese (No more than 2 mg. USDA researchers report that elevated manganese, more than 20 mg daily, competes with magnesium uptake in the heart causing irregular heart beats.)
  

  Manganese alters mitochodrial integrity in the hearts of swine marginally deficient in magnesium … These results suggest that high Mn, when fed in combination with low Mg, disrupts mitochondrial ultrastructure and is associated with the sudden deaths previously reported.

• Supplement the amino acids Taurine, Arginine and Carnitine (1 to 3 g).
• Avoid supplemental calcium.
• Add a good mineral/multivitamin – to cover all possible nutritional needs.

The following link to the Pauling Therapy and Video provides the scientific rationale for the Linus Pauling vitamin C/lysine therapy on a 1 hour video:
http://www.paulingtherapy.com

SUMMARY

The unified theory explains that heart disease, as do many natural healing processes, begins only after a stress fracture appears on the wall of an artery. The Lp(a) molecule is attracted to remnants of a broken collagen strand within the fracture. The most probable cause for lesions forming in a pattern so familiar to Willis is the mechanical stress caused by the beating heart. Dr. Willis theorized that heart disease was ultimately a vitamin C deficiency.

Most animals do not have Lp(a) in their blood, Lp(a) acts as a surrogate for vitamin C, extending life in the few species unable to synthesize ascorbate. Lp(a) binds to “lysyl” residues and in this way forms plaque. The Lp(a) molecule itself was discovered circa 1964 and was unknown to Willis. Lp(a) has a similar molecular weight to LDL cholesterol and most studies grouped it with LDL prior to 1989. Recently a reevaluation of these studies found that Lp(a) and not ordinary LDL is highly predictive of CVD and that elevated Lp(a) increases the risk of heart attack and stroke by 70%.

The on-going lack of scientific curiosity or interest by organized medicine in the Pauling/Rath theory and Pauling’s high-dose therapy may well be recognized as the greatest lapse of the 20th century.

Owen Fonorow, Naturopath, Ph.D.
Vitamin C Foundation
PO Box 3097, Lisle IL 60532
www.VitaminCFoundation.org
630-416-1438

PaulingTherapy.com

REFERENCES AND RECENT SCIENTIFIC SUPPORT FOR THE UNIFIED THEORY

Harvard Nurses Study

The 15-year Harvard study of 85,000 nurses found that a single vitamin C pill reduces the incidence of heart disease by almost 30%. According to the numbers in  A 360 mg vitamin C pill daily would save more than 300,000 lives per year.

British/Enstrom CVD Mortality Findings

In 1992 Dr. James E. Enstrom of the UCLA School of Public Health, published his latest research on how men taking vitamin C, about 300 milligrams or more per day, on average live six years longer than those who receive less than 50 milligrams of vitamin C daily. In late 2003, British researchers confirmed the finding that low vitamin C is related to higher CVD mortality. (They found no relationship between either vitamin E or vitamin A and mortality.)

CVD Mortality Curves

It is not controversial that total mortality from all forms of heart disease peaked between the years 1950 and 1970, and that deaths from coronary heart disease peaked around 1970. It is interesting that in 1970, Nobelist Linus Pauling published his best-selling book Vitamin C and the Common Cold. 

Oxford meta analysis of 27 clinical studies

A meta-analysis of 27 large studies (09/04/2000) at Oxford University found that people with high Lp(a) are 70% more likely to have a heart attack or stroke than people with normal or low Lp(a). 

JAMA Jan 23/30 2002 RANDOMIZED, DOUBLE-BLIND CONTROLLED TRIAL IN HUMANS FOUND STATISTICALLY SIGNIFICANT 60-SECOND TREADMILL EXERCISE IMPROVEMENTS IN 5000 MG VITAMIN C GROUPS

[Chelation Therapy for Ischemic Heart Disease: A Randomized Controlled Trial, Knudtson, et. al. JAMA, Jan 23/30, 2002 – Vol 287, No 4. Pp 481-486]

Vitamin C transforms stem cells into heart muscle

Stem cells, undifferentiated cells that can become other cells, have become the subject of intense scientific research. Patients given their own stem cells have avoided heart transplants, according to recent news stories, and stroke patients have recovered more quickly after being given stem-like cells. See this [ article ] on the Harvard finding that only 1 of 880 substances tested – vitamin C – converted mouse stem cells into heart muscle.

Genetically-engineered Mice

Mice, like most other mammals, produce their own engodenous vitamin C, so experiments with these creatures usually have little to say about chronic scurvy in humans. Scientists recently engineered a strain of mice that are unable to synthesize ascorbate. 

1700+ studies show Lp(a) is a major CVD risk factor

There are few studies of Lp(a) in the MEDLINE medical database prior to 1989, the year Pauling began his lecture tour. Since 1989, the Lp(a) science has exploded. There are now more than 1700 studies and articles that have investigated Lp(a). 

Cholesterol drugs do not lower Lp(a) and some raise it

A little known fact is that the top-selling statin cholesterol drugs actually cause Lp(a) to increase! See this [ article ] for more information on the dangers in the popular statin drugs.

CoQ10 connection

There are several reports of the remission of congestive heart failure in heart patients who have adopted Pauling’s therapy. It is known that CoQ10 is a good treatment for this condition, and it is known that vitamin C is required for the body to synthesize CoQ10. See this [ article ] for more information on the vitamin C and CoQ10 connection.

The post Cure For Heart Disease – True Testimonial appeared first on Alternative Complementary Medicine.

10 years after Dr. Rath had first published his landmark discovery it is recognized as the key discovery towards the control of cardiovascular disease. The invitation of Stanford University for Dr. Rath reflects the fact that the world’s leading medical institutions can no longer ignore this medical breakthrough.

DR. RATH’S PRESENTATION AT STANFORD UNIVERSITY

The Scurvy – Heart Disease Connection

Solution to the Puzzle of Cardiovascular Disease
Palo Alto , California , May 4, 2002

I would like to congratulate Stanford University for addressing the need for preventive and natural answers to the number one cause of death in the industrialized world. I will present to you the facts that atherosclerosis, heart attacks and strokes are not diseases but the direct result of long-term vitamin deficiency. And therefore they can be prevented by natural means, without pharmaceutical drugs or surgical intervention.

Heart Disease is an early form of the sailor’s disease scurvy.
All existing hypotheses of atherogenesis have one problem in common – they defy human logic. The theory that high cholesterol levels, oxidized LDL or bacteria damage the vascular wall would lead to the formation of atherosclerotic plaques along the entire vascular pipeline. Inevitably, peripheral vascular disease would be the primary manifestation of cardiovascular disease. This is clearly not the case. It doesn’t require a degree from Stanford or any other medical school – any lay person can solve the Plumber’s riddle . The arteries, veins and capillaries in our body are a pipeline that is 60,000 miles long. But this pipeline fails in 90% of the cases at one specific spot: The coronary arteries, with the length of only one billionth of the total vascular pipeline. If bad water quality – e.g. high cholesterol – would cause damage to this pipeline, it would clog everywhere, not just at one spot. Obviously, elevated cholesterol can not be the cause of coronary artery disease.

The solution to the puzzle of cardiovascular disease, therefore, must lie in the explanation of coronary artery plaques as the predominant manifestation of cardiovascular disease .

To solve this puzzle we need to refocus our attention away from the blood stream and its constituents towards the one and only relevant target: the stability of the vascular wall.
As opposed to animals, the human body cannot synthesize vitamin C. Ascorbate deficiency results in two distinct morphological changes of the vascular wall: Impaired vascular stability due to decreased collagen synthesis and loss of the endothelial barrier function.

The sailors of earlier centuries died within a few months from hemorrhagic blood loss due to lack of endogenous ascorbate synthesis combined with a vitamin deficient diet aboard. When the Indians gave those sailors tea from tree barks and other vitamin rich nutrition, blood loss was stopped and the vascular wall healed naturally.

Today, everyone gets some vitamin C and open scurvy is rare. But almost everyone suffers from chronic vitamin deficiency. Over decades, micro lesions develop in the vascular wall, especially in areas of high mechanical stress such as the coronary arteries.

Just as in the sailor’s disease scurvy, so does vitamin C induce the natural repair of the blood vessel wall in cardiovascular disease leading to a halt in progression and even to natural regression of vascular lesions.

In contrast to current models of atherogenesis, the Scurvy / Heart Disease Connection can answer all key questions in clinical cardiology today.

Why do we get infarctions of the heart and not the nose or ears?
The answer can be reduced to two factors: Structural impairment of the vascular wall due to vitamin deficiency combined with the mechanical stress from pastille blood flow in the coronary arteries. It is at this unique spot where the underlying structural impairment is exposed first.

Why do we get arteriosclerosis, but not venosclerosis?
The cholesterol and the infection theory would inevitably lead to clogging of veins and capillaries. The scurvy heart disease connection provides the only logical answer to this phenomenon. Why animals don’t get heart attacks, but people do? Why do bears and other hibernators with cholesterol levels of 600 mg/dl are not extinct from an epidemic of heart attacks? The answer: Animals produce their own vitamin C in amounts between 1 gram and 20 grams each day, compared to the human body weight. These amounts of ascorbate are obviously sufficient to optimize the stability of their vascular walls without any necessity for Statins.

Why are all important risk factors for CVD closely connected to ascorbate deficiency , including, diabetes, hyperlipdemia, homocysteinuria and others.
The common denominator of these metabolic disorders is to provide compensatory stability for the vitamin deficient vascular wall. This is also the reason, why ascorbate deficiency increases fibrinogen and thromboxane levels while decreasing endothelial derived relaxing factor (NO) and prostacyclin.
L ets turn to key evidence for the scurvy / heart disease connection. The guinea pig, like man, cannot synthesize ascorbate endogenously. In our published research we demonstrated that, when guinea pigs are fed vitamin C only at the level of the human RDA they develop atherosclerosis. These vascular lesions are histologically indistinguishable from human atherosclerotic plaques. In contrast, the control animals receiving Vitamin C levels of one teaspoon vitamin C per day have clean arteries.

These experiments were confirmed by Meade et al. in an ascorbate “knock out” animal model. The first manifestation in these animals was the deterioration of the vascular wall, resembling early atherosclerosis in man. We confirmed these results in a clinical study in patients with preexisting coronary artery deposits measured by Ultrafast Computed Tomography. Following a defined vitamin program, the progression of calcification significantly decreased and in some cases the disappearance of lesions was documented, as you can see in this X-ray CT pictures. Copies of the publication of this clinical study are available at this meeting or online.

The scurvy heart disease connection means a paradigm shift in medicine from symptom-orientation to the only relevant preventive and therapeutic target: The stability of the vascular wall . With the discovery of the scurvy / heart disease connection, the “world of heart disease” has ceased to be a plate and has become a globe.

Now that we have identified the true nature of cardiovascular disease, its eradication is only a question of time. Already in ten years from now the headlines of the leading newspapers may read: “WHO proclaims heart disease as eradicated / The pharmaceutical market of statins and other symptom-oriented drugs have collapsed on Wall Street / and the cardiology departments at Stanford and other Medical Schools are closing”.

On behalf of millions of patients with heart diseases I call upon Stanford University and other medical institutions to accept their responsibility and join us in the eradication of cardiovascular disease.

Source: www4.dr-rath-foundation.org/